Papers by Nikita Nikita

39 results

  1. Journal of Evolutionary Biology

    Death risk rose with age in asexual Hydra oligactis

    The maximum observed lifespan was approximately two years in a laboratory experiment comparing animals fed five times per week with those fed three times.The maximum observed lifespan was approximately two years in a laboratory experiment comparing animals fed five times per week with those fed three times.

    Experiments in hydraInterventions
  2. JAMA Cardiology

    Global heart failure cases reached 56 million in 2023

    A Global Burden of Disease analysis across 204 countries estimated 56.0 million prevalent heart failure cases in 2023, with rates generally increasing with age.A Global Burden of Disease analysis across 204 countries estimated 56.0 million prevalent heart failure cases in 2023, with rates generally increasing with age.

    Computational studyHeart failure
  1. medRxiv

    Genetic scores add more predictive power at lower clinical risk

    For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with 4.9-fold higher incidence…For atherosclerotic cardiovascular disease, polygenic risk expanded the clinically identified high-risk subgroup by 40%, revealing patients with 4.9-fold higher incidence than those remaining low-risk.

    Preprint: cohort study of 900,000 peopleBiomarkers
  2. International Journal of Molecular Sciences

    ADA loss impairs DNA repair and spurs senescence in astrocytes

    Studying sporadic ALS astrocyte models, researchers found TDP43 dysfunction impaired adenosine deaminase, disrupting purines and raising P16 levels while blunting…Studying sporadic ALS astrocyte models, researchers found TDP43 dysfunction impaired adenosine deaminase, disrupting purines and raising P16 levels while blunting 53BP1-mediated repair.

    Experiments in human cellsDNA repair