Papers by Lei Huang

The Journal of Nutrition, Health & Aging4 Oct
Metabolic signature links frailty to coronary artery disease
A 36-metabolite signature mediated an estimated 18.5% of the association between frailty and incident coronary artery disease over a median 14.8-year follow-up.A 36-metabolite signature mediated an estimated 18.5% of the association between frailty and incident coronary artery disease over a median 14.8-year follow-up.
Cohort study of 223,907 peopleCoronary artery disease
Paper
BMC Public Health2 Oct
Heatwaves linked to declining intrinsic capacity in older adults
Each additional heatwave day was linked to a relative risk ratio of 1.035 for a low-declining intrinsic capacity trajectory, while cold spells showed no association.Each additional heatwave day was linked to a relative risk ratio of 1.035 for a low-declining intrinsic capacity trajectory, while cold spells showed no association.
Cohort study of 1,393 peoplePopulations
Paper
Molecular Systems Biology28 Sep
Engineering a compact CgCas12n platform for efficient genome and base editing in mammalian cells
Experiments in cellsInterventions
Paper
Experimental Gerontology17 Sep
Handgrip strength asymmetry and cardiometabolic multimorbidity in Chinese middle-aged and older adults: a longitudinal cohort study
Cohort study of 8,132 peopleCardiometabolic multimorbidity
Paper

Research Square11 Sep
Multi-Expert Measurement-Aware Learning for Carotid Intima-Media Complex Segmentation and Thickness Quantification in Ultrasound Images
Preprint: computational studyBiomarkers
Paper
Environment International11 Sep
Beyond annual dose: Assessing lifetime cancer risk from dietary radiocesium exposure and public risk-perception gaps in Japan
Computational studyPopulations
Paper
Materials Today Bio10 Sep
Elucidate the structural role of helper lipids in modulating hepatic expression following repeated intravenous administration of mRNA-LNPs
Experiments in animalsInterventions
Paper
Ecotoxicology and Environmental Safety6 Sep
Multi-level evidence for Pb-Cd co-exposure nephrotoxicity: An integrated analysis of NHANES, outcome-oriented network toxicology, and cell-based validation
Cross-sectional study of 5,049 peopleMechanisms
Paper
Journal of Rehabilitation Medicine4 Sep
Relative fat mass predicts symptomatic knee osteoarthritis in older adults with metabolic syndrome: a longitudinal cohort study
Cohort study of 3,301 peopleKnee osteoarthritis
Paper
Experimental and Therapeutic Medicine21 Aug
Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial
Trial in peopleInterventions
Paper
Research Square20 Aug
Robust and Interpretable Metagenomic Modeling Through Structure-Aware Multi-View Learning and Attribution-Guided Biological Insight
Preprint: study of 1,990 peopleDeep learning
Paper
Journal of Cellular Physiology10 Aug
Simulated Microgravity Induced Mesenchymal Stem Cell Senescence via the Activation of Cytosolic mtDNA-cGAS-STING Axis
Experiments in rat cellscGAS–STING signalling
Paper