Papers by Gang Chen · AgingResearch.News

Reviews in the Neurosciences7 Oct
Microglial lipid metabolism in perioperative neurocognitive risk: aging-related priming, organelle crosstalk, and lipid-redox injury
ReviewLipid and ceramide metabolism
Paper
Aging Cell2 Oct
Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice
TNF-alpha triggers a mitochondrial immune pathway via Prodh2 that damages myoblasts, while silencing the enzyme restores muscle strength in mice.TNF-alpha triggers a mitochondrial immune pathway via Prodh2 that damages myoblasts, while silencing the enzyme restores muscle strength in mice.
Experiments in miceMuscle
Paper
Research Square1 Oct
Generative Artificial Intelligence, Health Risk Perception Bias, and Sports Participation Among Older Adults —An Empirical Investigation Grounded in the Search-as-Learning Paradigm
Preprint: cohort study in peoplePopulations
Paper
Frontiers in Neurology30 Sep
The association of high-sensitivity C-reactive protein-triglyceride glucose index with functional outcome in elderly patients with acute ischemic stroke undergoing intravenous thrombolysis
Cohort study of 708 peopleAcute ischemic stroke
Paper

Journal of Immunology28 Sep
Mechanism of SGLT2 inhibitors in improving immune imbalance in diabetic mice with sepsis via regulating macrophage M2 polarization through the APOC1/HMGB1/TLR4 axis
Experiments in miceSGLT2 inhibitors
Paper
Frontiers in Immunology24 Sep
Evaluation of primate anti-pig xenoreactive immune responses using immortalized aortic endothelial cells from genetically modified pigs
Experiments in pig cellsBlood and immune system
Paper
World Journal of Oncology13 Sep
Association Between Sleep Disorders and Breast Cancer: An Analysis Based on NHANES and Mendelian Randomization
Mendelian randomisation in 8,366 peopleSleep disorders
Paper
Journal of Human Hypertension5 Sep
Using electronic clinical decision support in primary care to enhance identification of primary aldosteronism: a protocol for the CONSEP cluster-randomised controlled trial
Study protocolInterventions
Paper
Chemico-biological Interactions28 Aug
SIRT6/RXRα/retinoic acid-related signaling contributes to intestinal stem cell homeostasis during aging and is modulated by Atractylenolide II
Experiments in miceGut and microbiome
Paper
Research13 Aug
An Emodin-Depot Microsphere-in-Hydrogel Reprograms the Immuno-myogenic Niche to Enable Volumetric Muscle Loss Repair Revealed by Single-Cell Profiling
Experiments in animalsInterventions
Paper
medRxiv12 Aug
A Deep Learning-Derived Insulin Resistance Index for Cardiovascular Risk Prediction: A Prospective Cohort Study with External Validation in Chinese and US Populations
Preprint: cohort study of 13,889 peopleCardiovascular disease
Paper
JACC Asia12 Aug
Lifestyle and Metabolic Health, Low-Grade to Clinically Elevated Albuminuria, and Cardiovascular-Renal Diseases
Cohort study of 82,509 peopleCardiovascular disease
Paper
Research Square6 Aug
An ADSCs-loaded Intelligent Delivery System Based on PLGA- PEG-PLGA Hydrogel for Promoting Anterior Cruciate Ligament Regeneration in Rabbits
Preprint: experiments in animalsInterventions
Paper
Food and Chemical Toxicology6 Aug
Endocrine-disrupting chemical-induced gene networks confer coronary heart disease risk revealed by causal inference and single-cell analyses
Study in peopleMechanisms
Paper
HLA4 Aug
Antibody Responses Against Swine Leukocyte Antigens Contribute to Early Rejection After Pig-To-Monkey Kidney Xenotransplantation
Experiments in 13 monkeysImmune response
Paper
ADA Scientific Sessions 2026 Abstract5 Jun
Discovery of Selective, Long-Acting Amylin Receptor Agonist for Obesity
Experiments in animalsInterventions
Paper
ADA Scientific Sessions 2026 Abstract5 Jun
Discovery and Development of CH3127, a Prodrug of Semaglutide for Once Weekly Oral Tablet Dosing
Experiments in animalsInterventions
Paper
ENDO 2025 Abstract23 Oct
SUN-263 Association of Oxidative Balance Scores with Cardiovascular-Kidney-Metabolic Syndrome Risk and All-Cause Mortality: Evidence from NHANES 2005-2017
Study in peoplePopulations
Paper