MechanismsAnimals

Age linked to more diverse gut bacteria in bonobos

An observational study of 165 wild and zoo-housed bonobos aged 2 to 71 years found age-related patterns resembling those seen in humans.

Figure 1 from NPJ Biofilms and Microbiomes
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Figure 1Torfs et al.

NPJ Biofilms and Microbiomes

In an observational study, researchers characterised gut bacteria in 165 bonobos (Pan paniscus), aged 2 to 71 years, from wild and zoo-housed populations. In both settings, older age was associated with greater bacterial diversity. Core bacterial groups, those typically shared across individuals, were less abundant, while rarer groups increased.

Bacterial communities became less stable and more distinct between individuals with age in zoo-housed bonobos, but not in wild bonobos. This mirrored patterns restricted to industrialised human populations. Cumulative exposure to different environments over a lifetime was also linked to how distinctive an individual’s gut bacterial community was.

Why it matters

The comparison helps researchers ask which features of human gut bacterial aging are shared among great apes and which may depend on lifetime environmental exposures.

Caveats

The observational design cannot establish that environmental exposures caused the age-related differences. The findings came from bonobos, not people.

The paper

Ageing processes in the bonobo gut microbiome mirror human patterns