MechanismsHumans22 participantsCross-sectional study

Older adults with muscle weakness had less steady force

A measure of force variability rose about 35% when adults with muscle weakness subtracted numbers during ankle contractions, compared with the muscle task alone.

A lower leg cutaway beside muscle bundles with dense, orderly fibres above sparse, irregular fibres, and a brain below.

Journal of Cachexia, Sarcopenia and Muscle

In an observational study, 11 older adults with sarcopenia, 22 adults without it and 19 older athletes performed ankle contractions. Participants averaged 74.3 years of age; half were female. Researchers defined sarcopenia, a condition involving muscle weakness, by low grip strength and slow walking speed. Participants held contractions at 30% of their maximum turning force, either while subtracting numbers or without a mental task. Electrical recordings from muscles allowed researchers to assess the timing of signals activating muscle fibres.

The sarcopenia group produced less steady force than both comparison groups during both tasks. Their force variability rose about 35% when they also subtracted numbers. The intervals between signals activating muscle fibres became more variable in this group during the combined task. That timing measure stayed unchanged in controls and became less variable in athletes.

Why it matters

Sarcopenia is associated with impaired physical function in older age. The findings support expanding muscle-centric views of the condition to include neural mechanisms when studying how to preserve mobility.

Caveats

The observational group comparison cannot establish that sarcopenia caused the differences in control. Only 11 participants had sarcopenia, and the researchers measured performance during a specific laboratory task.

The paper

Dual-Tasking Exacerbates Force and Neural Control Unsteadiness in Older Adults With Sarcopenia

The University of Queensland · Deakin University

Journal of Cachexia, Sarcopenia and Muscle · 1 Oct 2026

doi.org/10.1002/jcsm.70397PubMed 42833644