Reproducible human reward imaging phenotypes exhibit differential sensitivity to dopamine D2 receptor antagonism

Nature Communications

The paper

Nicola Sambuco, Antonella Lupo, Peter C.T. Hawkins,

Pierluigi Selvaggi, Linda Antonella Antonucci, Alessandro Bertolino, Giuseppe Blasi, Piergiuseppe Di Palo, Luigi Grassi, Daniela Grasso, Philipp Homan, GianMarco Leggio, Francesco Massari, Alessio Maria Monteleone, Martin Osugo, Roberta Passiatore, Alessandra Raio, Antonio Rampino, Tobias Banaschewski, Gareth Barker, Arun L.W. Bokde, Ruediger Bruehl, Sylvane Desrivières, Herta Flor, Hugh P Garavan, Penny Anne Gowland, Antoine Grigis, A. Heinz, Jean‐Luc Martinot, Marie‐Laure Paillère Martinot, Éric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Michael N. Smolka, Nathalie E. Holz, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Gunter Schumann, Apulian Network On Risk For Psychosis, Oliver Howes, Mitul Ashok Mehta,

Giulio Pergola

University of Bari Aldo Moro · Johns Hopkins University

Nature Communications · 3 Sep 2026