NatureTargeted genomic integration and rearrangement using prime assemblyBy Sébastien Levesque, Nozomu Kawashima, Gue-Ho Hwang, +9Show 9 more authors, Daniel E. BauerExperiments in cellsInterventionsPaperThe paperSébastien Levesque, Nozomu Kawashima, Gue-Ho Hwang, +9Show 9 more authors, Jing Zeng, Vasil Toskov, Timothy Barry, William P. Mannherz, Luke Homfeldt, Basheer Becerra, Vivien A. C. Schoonenberg, Luca Pinello, Suneet Agarwal, Daniel E. BauerBroad InstituteNature, 16 Sep 2026doi.org/10.1038/s41586-026-11024-2PubMed 42749803
Nature Communications·2 Oct 2026Base editing of the lamin farnesylation motif rescues progeria phenotypes in organoids