The Lancet Diabetes & Endocrinology

Efficacy and safety of once-weekly semaglutide 2·4 mg in Chinese adults with overweight or obesity (STEP 12): a randomised, double-blind, placebo-controlled, multicentre, phase 3b trial

Randomised trial in 242 peopleInterventions

44 weeks, double-blind, placebo-controlled, multicentre, registered NCT06041217

The paper

Chinese Academy of Medical Sciences & Peking Union Medical College; Northwestern University

The Lancet Diabetes & Endocrinology, 10 Aug 2026

doi.org/10.1016/s2213-8587(26)00133-6PubMed 42575111