Nature Medicine
Large-scale whole-genome sequencing reveals the landscape and health implications of de novo mutations
Cohort study of 24,030 peoplePopulations
- In vitro embryo manipulation
- Intracytoplasmic sperm injection
- Ovarian stimulation
- De novo mutations
- Maternal dnSNVs
- Humans
The paper
State Key Laboratory of Reproductive Medicine; Suzhou Municipal Hospital
Nature Medicine, 7 Aug 2026