The Journal of Neuroscience

More precise brain patterns linked to better learning in adults

Among 251 younger and older adults, 76 underwent brain scans that linked more precise representations of choices to better learning.

Cross-sectional study of 76 younger and older adultsMechanisms

251 participants, cohort study

Limit: Brain-scan results relied on only 76 participants

Edited by Boris Djordjevic · AgingResearch.News

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In an observational study, 251 younger and older adults—158 women and 93 men—learned the values of four houses through trial and error. Of these, 76 completed the task while undergoing brain scans. Older adults performed less accurately.

Among scanned participants, more precise representations of the houses in the posterior hippocampus, the rear part of a brain region involved in memory, were associated with greater accuracy across age groups. The researchers found no evidence that these representations were less precise in older adults. Older adults instead showed less closely linked activity between this region and the medial prefrontal cortex, a brain area involved in decision-making. The strength of this link correlated with accuracy.

Why it matters

The work addresses whether age-related differences in learning the value of choices reflect less precise brain representations or altered links between brain regions.

Caveats

Comparing younger and older groups does not show how the same individuals change as they age. Brain-scan findings came from 76 participants, not the full sample.