Developmental Cell

A PBX/MEIS Complex Balances Reproduction and Somatic Resilience

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Abstract

Resource reallocation to metabolic processes promoting reproduction is critical for the survival of a species and therefore is tightly regulated. In this issue of Developmental Cell, Dowen (2019) finds that a PBX/MEIS homeodomain transcription factor complex controls a transcriptional network that balances reproduction versus longevity and somatic maintenance.

The paper

University of Freiburg; Princeton University

Developmental Cell, Apr 22, 2019, Open access

doi.org/10.1016/j.devcel.2019.04.005PubMed 31014476