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Frontiers in Endocrinology

Evening exercise may aid arteries in older adults with type 2 diabetes

In a 12-week randomized trial of 66 older adults with type 2 diabetes, an exploratory comparison favored evening over morning exercise for artery stiffness.

Paper by Zhiying Ma, Yanyu Lin, Zheng Zhu, Zhenbo Cao · Shanghai University of Sport
Figure 1 from Frontiers in Endocrinology
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Figure 1. Ma et al., CC BY
Randomized trial in 58 older adults with T2DM, 12 weeks, against morning exercise participantsInterventions

Registered ChiCTR2300073737

Limit: Lipid-lowering medication use differed between groups and could have influenced vascular responses

Edited by Boris Djordjevic · AgingResearch.News

Paper
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In a randomized trial, 66 older adults with type 2 diabetes were assigned to morning exercise, evening exercise or a control group, with 22 in each. The exercise groups received online, moderate-intensity aerobic and resistance exercise three times weekly for 12 weeks. Morning sessions ran from 9:00 to 10:10; evening sessions ran from 19:00 to 20:10. Controls maintained their usual lifestyle and attended weekly health education sessions.

The final analysis included 58 participants. Both exercise groups improved a measure of blood vessel widening and reduced blood pressure and artery stiffness from baseline. An exploratory comparison found a greater reduction in artery stiffness with evening exercise than with morning exercise. The authors concluded that timing may influence blood vessel responses to exercise, with evening sessions potentially offering additional benefits, particularly for artery stiffness.

Why it matters

Blood vessel dysfunction is linked to cardiovascular disease risk in type 2 diabetes. The trial addressed whether exercise timing matters for blood vessel health in older adults.

Caveats

Direct comparisons between exercise times were exploratory, and the final analysis included 58 of the 66 randomized participants. The results concern older adults with type 2 diabetes; the abstract does not report cardiovascular events or adverse events.

From the paper

Participants

We enrolled 66 eligible participants and randomly assigned them to three groups (n = 22 each).

Results, 3.1 Participant characteristics

Limitation

First, owing to practical constraints, we did not include an afternoon exercise group.

4 Discussion

Quoted word for word from the full text on frontiersin.org.

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