ADA Scientific Sessions 2025 Abstract

Antibody-siRNA Conjugate Targeting Myostatin Preserves Muscle Mass during GLP-1R Agonism

By Yafei Xing, Yue Wu, Xuefeng Zhang, Hao Wu

Experiments in animalsInterventions

The paper

Yafei Xing, Yue Wu, Xuefeng Zhang, Hao Wu

Shanghai

ADA Scientific Sessions 2025 Abstract, 13 Jun 2025

Presented at ADA Scientific Sessions 2025, late-breaking 2185-LB

doi.org/10.2337/db25-2185-lb

Cell Metabolism8 Oct 2026
A triple-target drug cut body weight by up to 19.7% in a trial
JCI Insight6 Oct 2026
Antibody reduced fat while preserving lean mass in mice
The New England Journal of Medicine4 Oct 2026
Survodutide reduces weight in adults with diabetes and obesity
The New England Journal of Medicine4 Oct 2026
Retatrutide reduces weight and pain in adults with obesity