INVESTIGATING DRUG-INDUCED DEMENTIA IN A CNS MPS ASSESSING DEFICITS IN LTP FROM ANTICHOLINERGIC COGNITIVE BURDEN

Abstract

Microphysiological systems (MPS) provide an avenue for small-scale modelling of organ constructs. In conjunction with human induced-pluripotent stem cells (hiPSCs) cultured on microelectrode arrays (MEAs), MPS enable the exploration of functional deficits in concurrence with drug efficacy.

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