GSA 2024 Abstract

IMPACT OF ALZHEIMER’S DISEASE ON SUPRACHIASMATIC NUCLEUS CONNECTIVITY, SLEEP REGULATION, AND CIRCADIAN RHYTHM

Experiments in animalsMechanisms

Abstract

Circadian disruption, notably sleep disturbances, serves as an early indicator of Alzheimer’s disease (AD), preceding cognitive symptoms such as memory impairment. Despite this, the underlying anatomical and functional mechanisms driving circadian disruption in AD remain elusive.

The paper