ASSOCIATION OF PHYSICAL ACTIVITY WITH NEUROFILAMENT LIGHT IN NONDEMENTIA OLDER ADULTS AND THE MEDIATION OF FRAILTY

Abstract

Neurofilament light (NfL) is a biomarker for neuronal health, indicative of neural damage and decline in older adults. Physical activity (PA) is known to promote healthy aging and prevent frailty. However, the interplay between PA, physical frailty, and NfL remains underexplored.