Nature Communications

Sub-stoichiometric degradation is dispensable for potent PROTACs as demonstrated by irreversible covalent BTK degraders

By Ran Cheng, Hanfeng Lin, Xin Yu, Yi-Xiang Wang

Experiments in cellsInterventions

The paper

Ran Cheng, Hanfeng Lin, Xin Yu, Yi-Xiang Wang

Baylor College of Medicine

Nature Communications, 7 Oct 2026, CC BY-NC-ND

doi.org/10.1038/s41467-026-78239-9

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