AAIC 2025 Abstract
Tau exacerbates the development of motor disturbances but has no effect on the development of irritability across the Braak stages – The HEAD Study
By Cristiano Schaffer Aguzzoli, Guilherme Povala, Pâmela C.L. Ferreira, Show 20 more authorsTharick Ali Pascoal
Study in peopleMechanisms
Abstract
Background: Previous studies demonstrated an association between tau pathology and the development of neuropsychiatric symptoms (NPS) in individuals with Alzheimer’s disease (AD). However, the extent to which tau influences each specific NPS domain remains unclear.



