Alzheimer’s Polygenic Risk Scores Associate with Atherogenic Lipids and Reduced CRP in Mid‐Life Women

Abstract

Background: Metabolic and inflammatory dysregulation are increasingly implicated in Alzheimer’s disease (AD) aetiology. Genome‐wide association studies link AD risk loci to lipid metabolism and innate‐immune pathways, yet it remains unclear how polygenic burden manifests in peripheral biomarkers.

The paper