Interictal Epileptiform Discharges and Alzheimer's Disease‐Associated Cortical Atrophy in Late‐Onset Epilepsy of Unknown Etiology

Abstract

Background: Late‐onset epilepsy of unknown etiology (LOEU) is associated with elevated dementia risk and may reflect early pathological changes from Alzheimer’s disease. We assessed for relationships between interictal epileptiform discharges on EEG, patterns of cerebral atrophy, and subsequent development of dementia in LOEU.