MechanismsHumans
7T MRS Glutamate and GABA in Alzheimer’s Disease
AAIC 2025 Abstract
Abstract
Background: Functional neuroimaging studies suggest a dynamic trajectory in Alzheimer’s disease (AD), with early hyperconnectivity followed by hypoconnectivity due to pathologic progression. This study aimed to investigate this hypothesis using neurochemical markers derived from high‐field magnetic resonance spectroscopy (MRS).
The paper
Laura Göschel, Andrea Dell’Orco, Bernd Ittermann, Ariane Fillmer
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Charlotte Elisabeth Teunissen, Patty L. Hoede, Jeanette Melin, Leslie Pendrill, Sebastian Niclas Roemer, Nicolai Franzmeier, Pèter Köertvelyessy, Agnes Flöel,Humboldt-Universität zu Berlin · Physikalisch-Technische Bundesanstalt
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025
