AAIC 2025 Abstract

PRImus‐AD study: Design of the phase 2 study treating patients with MCI or mild dementia due to Alzheimer’s disease (AD) with the orally available PRI‐002

Trial in peopleInterventions

Abstract

Background: The drug candidate PRI‐002 is an all‐D‐enantiomeric peptide and was developed to disassemble toxic Aβ oligomers into harmless Aβ monomers. It is anticipated that PRI‐002 reduces neurotoxicity and restores synaptic plasticity in early stages of AD.

The paper