AAIC 2025 Abstract

Significance of Enrupatinib, a CSF1R inhibitor, on Decreasing Neuroinflammation and Maintaining Neuronal Health in Mice Models of Alzheimer's Disease

Experiments in animalsInterventions

Abstract

Background: A strong innate immune response, including microglial activation and high levels of inflammatory cytokines, is prevalent in Alzheimer's disease (AD), contributing to neuroinflammation, neuronal damage, and cognitive decline. Modulating microglial activity is therefore a promising therapeutic strategy.

The paper