Characterizing Tau Accumulation and Amyloid‐Tau Interactions in the Alzheimer’s Prevention Initiative Autosomal Dominant Alzheimer’s Disease Colombia Trial and Their Implications for Advancing Drug Development

Abstract

Background: Alzheimer’s disease (AD), particularly its autosomal dominant form (ADAD), presents unique challenges for drug development. Clinical trials involving cognitively healthy individuals with ADAD can provide a useful model for sporadic Alzheimer's disease.

The paper