AAIC 2025 Abstract
Effect of image‐processing and statistical harmonization methods on tau PET cognitive group separability for multisite cross‐sectional and longitudinal studies using ¹⁸ F‐Flortaucipir PET
By Weiquan Luo, Charles M. Laymon, Suzanne L. Baker, Show 3 more authorsAlzheimer’s Disease Neuroimaging Initiative
Study in peopleBiomarkers
Abstract
Background: Gaussian smoothing to a common resolution is regularly employed to harmonize PET imaging data acquired across different scanners in multisite studies. However, spatial smoothing of PET can increase spill‐over contamination between neighboring regions.
