Sex‐Differences in Association between Plasma GFAP and Cognition in Cognitively Unimpaired Community Dwelling Older Adults

Abstract

Background: Women are at greater risk of developing sporadic Alzheimer's disease (AD). While their longer lifespans contribute to AD‐risk, this factor does not fully explain the observed sex differences. Increased glial activation and neuroinflammation associated with female‐sex may play a role.