AAIC 2025 Abstract
The impact of brain energy metabolism‐related single nucleotide polymorphisms on Alzheimer's disease
By Gabriel Lermen Hoffmeister, Christian Limberger, Gabriel Bueno Martins, Show 3 more authorsEduardo Rigon Zimmer
Study in peopleMechanisms
Abstract
Background: FDG‐PET studies have demonstrated that glucose metabolism abnormalities can be detected up to a decade prior to the clinical onset of Alzheimer's disease (AD). This finding underscores that early metabolic alterations are fundamental to AD pathogenesis, rather than merely secondary to neurodegeneration.
