Differential Performance of p ‐tau217 in Reflecting Amyloid and Tau Stages in Cognitively Unimpaired and Impaired Individuals

Abstract

Background: This study aimed to assess the differential predictive performance of plasma p ‐tau217 for early and advanced stages of amyloid and tau pathology in cognitively unimpaired (CU) and cognitively impaired (CI) individuals, evaluating its stage‐specific utility across cognitive states.