Implementation of task‐based fMRI in TRAILBLAZER‐ALZ 6 Phase 3b study: Methodological considerations

Abstract

Background: Task‐based functional Magnetic Resonance Imaging (tb‐fMRI) leverages blood oxygenation to measure the brain's response to external stimuli. A lack of tb‐fMRI equipment standardization is the well‐recognized challenge when deploying this promising approach in multi‐center clinical trials.

The paper