Plasma Aβ40, Aβ42, Aβ42/40 ratio, tau, p ‐tau181, p ‐tau217 and NfL biomarkers to discriminate the prodromal stage of dementia along the continuum of cognitive impairment: Sex differences in the CompAS study

Abstract

Background: Plasma Aβ40, Aβ42, Aβ42/40 ratio, tau, p ‐tau181, p ‐tau217, and NfL have been proposed as possible valid early blood biomarkers for Alzheimer's Dementia (AD) (Simren et al., 2021). Although sex differences in some biomarkers (e.g., p ‐Tau‐181) were suggested in some studies (Tsiknia et al.