AAIC 2025 Abstract

Tau Cognitive Mismatch in Alzheimer's Disease Predicts Presence of Co‐Pathology and Diverging Disease Trajectory

Study in peopleBiomarkers

Abstract

Background: The revised Alzheimer's disease staging criteria use the concept of biological‐clinical mismatch with an expected, canonical progression; identifying individuals who have greater clinical impairment than expected for their biological stage as vulnerable or less impairment than expected as resilient.

The paper