MechanismsHumans
Sex‐specific genetic predictors of hippocampal volume in older adults
AAIC 2025 Abstract
Abstract
Background: Hippocampal volume is an important in vivo imaging marker for Alzheimer's disease (AD) risk and progression. Reported sex differences show accelerated hippocampal atrophy in females compared to males as AD‐related pathology increases.
The paper
Skylar Walters, Derek B. Archer, Kwangsik T. Nho, The Alzheimer's Disease Neuroimaging Initiative (ADNI); The Alzheimer's Disease Sequencing Project (ADSP)
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Andrew J. Saykin, Christos A. Davatzikos, Güray Erus, Shannon L. Risacher, Mohamad Habes, Di Wang, Reisa Anne Sperling, Mohamad J. Alshikho, Adam Brickman, Marilyn S. Albert, Anja Soldan, Yang An, Lori L. Beason‐Held, Murat Bilgel, Susan M. Resnick, Toshiko Tanaka, Keenan A. Walker, Sarah Biber, Walter W. Kukull, Lisa Laverne Barnes, David A. A Bennett, Philip L. De Jager, Vilas Menon, Julie A. Schneider, Corinne D. Engelman, Jason M. Fletcher, Sterling C. Johnson, Qiongshi Lu, Jie Song, L. Taylor Davis, Mary Ellen I. Koran, Dandan Liu, Kimberly R. Pechman, Niranjana Shashikumar, Angela Lee Jefferson, Timothy J. Hohman, Logan C. Dumitrescu,Vanderbilt University Medical Center
AAIC 2025 Abstract · 26 Dec 2025 · CC BY
Presented at AAIC 2025
