AAIC 2025 Abstract
Associations between Quantitative Neuronal Loss Measures and Postmortem MRI Atrophy Measures in the Human Medial Temporal Lobe in AD and LATE
By Paul A. Yushkevich, Sadhana Ravikumar, Laura E.M. Wisse, Show 28 more authorsAna María Insausti Serrano
Study in peopleBiomarkers
Abstract
Background: Medial temporal lobe (MTL) atrophy measured on MRI is a sensitive biomarker of AD‐linked neurodegeneration but is not specific to AD. LATE is a common AD co‐pathology that is challenging to distinguish from AD based on available validated biomarkers.


