Translational cognitive biomarkers for preclinical drug testing in neurodegenerative diseases

Abstract

Background: Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) are characterized by the accumulation of misfolded proteins, including amyloid‐β, tau, and alpha‐synuclein (a‐Syn). Despite extensive research, no effective disease‐modifying therapies exist.

The paper