AAIC 2025 Abstract
Plasma Alzheimer's mass spectrometry biomarkers associated with cerebrospinal fluid dynamics
By Camilo L Bermudez, Ekaterina I. Hofrenning, Jeffrey L. Gunter, Show 12 more authorsJonathan Graff-Radford
Study in peopleBiomarkers
Abstract
Background: Individuals with coexisting Alzheimer's disease (AD) and disorders of CSF dynamics such as normal‐pressure hydrocephalus (NPH) have lower CSF Aβ42 levels, which can confound interpretation of AD CSF‐biomarkers. However, little is known about how CSF dynamics influences plasma AD biomarkers.



