AAIC 2025 Abstract

Structure‐function decoupling in genetic frontotemporal dementia

Study in peopleMechanisms

Abstract

Background: Functional network integrity is important for maintaining cognitive performance during the 10‐20 year presymptomatic period of frontotemporal dementia (FTD), conferring resilience to advancing neuropathology and atrophy. The extent to which functional integrity relies on preserved structural connectivity is unclear.

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