AAIC 2025 Abstract
Evaluation of lithium carbonate treatment in a mouse model of Down syndrome using positron emission tomography
By Carolina Aparecida de Faria Almeida, Larissa Estessi de Souza, Chiara Maria Righini, Show 3 more authorsDaniele de Paula Faria
Experiments in animalsInterventions
Abstract
Background: Alzheimer's Disease (AD) is highly prevalent in people with Down syndrome (DS) due to the trisomy 21. As the life expectancy of people with DS has increased, new therapy strategies to delay the development of AD became an important area of research.


