AAIC 2025 Abstract

Glial inflammation in the posterior white matter modulates the amyloid‐tau‐cognition relationship

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Abstract

Background: White matter inflammation significantly contributes to the progression of Alzheimer's disease (AD). Changes in the translocator protein (TSPO), an in‐vivo marker of brain inflammation, have been observed in white matter (WM) through in‐vitro binding assays, immunostaining, and TSPO PET‐based quantification.

The paper