AAIC 2025 Abstract

Surgically induced brain‐draining lymphatic dysfunction accelerates the development of cognitive impairment

Experiments in animalsMechanisms

Abstract

Background: Mounting evidence suggests the involvement of the lymphatic system in the pathogenesis of Alzheimer's disease (AD). In this study, we examined the impact of brain‐draining lymphatic dysfunction on the cognition of wildtype (WT) and transgenic (TG) APP/PS1 mice.

The paper