Limbic‐predominant age‐related TDP‐43 encephalopathy, but Not Alzheimer's Disease, neuropathological changes are associated with Physical Performance Decline in the Oldest Old: Insights from The 90+ Study

Abstract

Background: To examine physical performance longitudinal trajectories in relation to Alzheimer's Disease Neuropathological Changes (ADNC) and Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathological changes (LATE‐NC) at autopsy.