AAIC 2025 Abstract

APOE Genotype Modulates Tau Propagation in A Novel Humanized Mouse Model of Early‐Stage Alzheimer's Disease

Experiments in animalsMechanisms

Abstract

Background: Possession of the apolipoprotein E e4 ( APOE4 ) allele remains the most significant genetic risk factor for developing the sporadic form of Alzheimer's disease (AD).

The paper