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Sex and apolipoprotein E (APOE) genotype Interact to impact relationships among sleep, Alzheimer's disease biomarkers, and memory in older adults
AAIC 2025 Abstract
Abstract
Background: Alzheimer's disease (AD) is characterized by tau and amyloid‐β (Aβ) pathologies, influenced by factors such as sex, aging, APOE genotype, and sleep. Sleep is essential for memory consolidation, but its interaction with these factors and AD biomarkers remains unclear.
The paper
Negin S. Sattari, Abhishek Dave, Kitty K. Lui, Ruth M. Benca
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Kate E. Sprecher, Miranda G Chappel-Farley, Ivy Y. Chen, Brady A. Riedner, Barbara B. Bendlin, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Henrik Zetterberg, Kaj Blennow, Bryce A. Mander,University of California, Irvine · Wake Forest University
AAIC 2025 Abstract · 24 Dec 2025 · CC BY
Presented at AAIC 2025

