Sex and apolipoprotein E (APOE) genotype Interact to impact relationships among sleep, Alzheimer's disease biomarkers, and memory in older adults

AAIC 2025 Abstract

Abstract

Background: Alzheimer's disease (AD) is characterized by tau and amyloid‐β (Aβ) pathologies, influenced by factors such as sex, aging, APOE genotype, and sleep. Sleep is essential for memory consolidation, but its interaction with these factors and AD biomarkers remains unclear.

The paper