AAIC 2025 Abstract

Phenotypic and Molecular Characterization of the LOAD2.Plcg2M28L Mouse Model Across Aging and Dietary Conditions

Experiments in animalsMechanisms

Abstract

Background: The LOAD2.Plcg2M28L mouse model presents a valuable tool for investigating late‐onset Alzheimer's disease (LOAD) by incorporating the PLCG2‐M28L variant, a genetic risk factor for developing LOAD.

The paper