PopulationsHumans
Rare Variant Association Analysis Reveals B3GNT9, RANBP10, and C1QL4 As Potential Genes for Cognitive Preservation in the Mid‐Western Amish
AAIC 2025 Abstract
Abstract
Background: Cognitive preservation is observed in older individuals who are at high risk of cognitive decline but remain cognitively unimpaired (CU). Identifying rare variants (RVs) associated with cognitive preservation may address the missing heritability of Alzheimer Disease (AD).
The paper
Yining Liu, Yeunjoo E. Song, Weihuan Wang, Jonathan L Haines
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Audrey H. Lynn, Kristy L. S. Miskimen, Sarada L. Fuzzell, Sherri D. Hochstetler, Reneé A. Laux, Laura J. Caywood, Jason E. Clouse, Sharlene D. Herington, Ping Wang, Alex V. Gulyayev, Leighanne R. Main, Daniel A. Dorfsman, Noel C. Moore, Michael B. Prough, Dawn McDougal Miller, Andrew F. Zaman, Larry Deon Adams, Patrice G. Whitehead, Paula K. Ogrocki, Alan J. Lerner, Jeffery M. Vance, Michael L. Cuccaro, William K. Scott, Margaret Pericak‐Vance,Case Western Reserve University
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025
