Tau pathology in the retina and its role in neurodegeneration

Abstract

The accumulation of abnormal phosphorylated tau ( p ‐τ) protein in neurons is a hallmark of Alzheimer's disease (AD) and primary tauopathies. Both conditions involve p ‐τ accumulation in retinal neurons. Here, we explore the role of p ‐τ pathology in visual performance and the interplay between retinal and cerebral p ‐τ pathology.

The paper