Modulation of Amyloid‐beta Metabolism by TIMP2 and MMP2 Through Extracellular Matrix Interactions in Mouse Models of Alzheimer's Pathology

Abstract

Background: Alzheimer's disease (AD) is characterized by several pathological processes, including amyloid‐beta (Aβ) accumulation and neuroinflammation, both of which have been linked to extracellular matrix (ECM) dyshomeostasis.