bioRxiv
Imputation-Based Harmonization Mitigates Site Effects Without Data Leakage in Machine Learning Studies
Preprint: computational studyAI & data
Abstract
Neuroimaging studies that pool data across clinical sites often suffer from site effects --- variability in imaging measures that arises from technical heterogeneity across sites as opposed to true biological signal.
The paper
University of Pennsylvania
bioRxiv, 5 Oct 2026, CC BY, Preprint, not peer-reviewed
