bioRxiv
Closed-Loop Auditory Stimulation Reveals Differential Sleep Oscillatory Contributions to Memory in Healthy Older Adults
Preprint: randomised trial in 16 peopleInterventions
Blinded, sham-controlled
Abstract
Sleep oscillations during non-rapid eye movement (NREM) sleep support memory consolidation but decline with age. Phase-locked auditory stimulation (PLAS) enhances slow-wave activity, yet its effects on distinct oscillatory components and memory in older adults remain unclear. Sixteen healthy older adults (60 years or older; mean age = 65.
- Closed-loop auditory stimulation
- Centrofrontal slow spindle
- Centroparietal fast spindle
- Creyos cognitive assessment battery
- Frontal theta
- Humans
The paper
Western University
bioRxiv, 20 Aug 2026, CC BY, Preprint, not peer-reviewed
