1:"/_next/static/immutable/chunks/365b61on5mcg4.js" 2:"/_next/static/immutable/chunks/1bdsvgxhdlloz.js" 3:"/_next/static/immutable/chunks/3i6_rfhwrc4o0.js" 4:"/_next/static/immutable/chunks/0f_7d7kh-cjld.js" 5:"HTTPAccessFallbackBoundary" 6:I[768017,["$1","$2","$3","$4"],"$5"] 16:I[168027,["$1","$2","$3","$4"],"default",1] :HL["/_next/static/immutable/chunks/27vwfpponrsnz.css","style"] :HL["/_next/static/immutable/chunks/1-5e-kxoox4o1.css","style"] :HL["/_next/static/immutable/media/3a11180d498b75c0-s.p.0ghexb8m2rs_v.woff2","font",{"crossOrigin":"","type":"font/woff2"}] 8:Tf7c,{"@context":"https://schema.org","@graph":[{"@type":"NewsMediaOrganization","@id":"https://agingresearch.news/#organization","name":"AgingResearch.News","alternateName":["Aging Research News","ARN"],"url":"https://agingresearch.news","logo":"https://agingresearch.news/logo.png","description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","slogan":"Every new aging paper, judged on evidence, never on fame.","foundingDate":"2026-10-02","parentOrganization":{"@type":"Organization","name":"Paperfoot AI Pte. Ltd.","address":{"@type":"PostalAddress","addressCountry":"SG"}},"publishingPrinciples":"https://agingresearch.news/status#standards","correctionsPolicy":"https://agingresearch.news/status#standards","ethicsPolicy":"https://agingresearch.news/status#standards","verificationFactCheckingPolicy":"https://agingresearch.news/status#standards","noBylinesPolicy":"https://agingresearch.news/status#standards","actionableFeedbackPolicy":"https://agingresearch.news/status#standards","contactPoint":{"@type":"ContactPoint","contactType":"editorial","url":"https://agingresearch.news/contact"},"knowsAbout":[{"@type":"Thing","name":"Aging","sameAs":"https://en.wikipedia.org/wiki/Ageing"},{"@type":"Thing","name":"Geroscience","sameAs":"https://en.wikipedia.org/wiki/Geroscience"},{"@type":"Thing","name":"Life extension","sameAs":"https://en.wikipedia.org/wiki/Life_extension"},{"@type":"Thing","name":"Cellular senescence","sameAs":"https://en.wikipedia.org/wiki/Cellular_senescence"},{"@type":"Thing","name":"Epigenetic clock","sameAs":"https://en.wikipedia.org/wiki/Epigenetic_clock"},{"@type":"Thing","name":"mTOR","sameAs":"https://en.wikipedia.org/wiki/MTOR"},{"@type":"Thing","name":"Rapamycin","sameAs":"https://en.wikipedia.org/wiki/Sirolimus"},{"@type":"Thing","name":"Cellular reprogramming","sameAs":"https://en.wikipedia.org/wiki/Reprogramming"},{"@type":"Thing","name":"NAD+","sameAs":"https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide"},{"@type":"Thing","name":"Sirtuins","sameAs":"https://en.wikipedia.org/wiki/Sirtuin"},{"@type":"Thing","name":"Mitochondria","sameAs":"https://en.wikipedia.org/wiki/Mitochondria"},{"@type":"Thing","name":"Calorie restriction","sameAs":"https://en.wikipedia.org/wiki/Calorie_restriction"},{"@type":"Thing","name":"GLP-1 receptor agonists","sameAs":"https://en.wikipedia.org/wiki/GLP-1_receptor_agonist"},{"@type":"Thing","name":"Inflammaging","sameAs":"https://en.wikipedia.org/wiki/Inflammaging"},{"@type":"Thing","name":"Brain aging","sameAs":"https://en.wikipedia.org/wiki/Aging_brain"},{"@type":"Thing","name":"Biological aging","sameAs":"https://en.wikipedia.org/wiki/Senescence"},{"@type":"Thing","name":"Geroprotectors","sameAs":"https://en.wikipedia.org/wiki/Geroprotector"},{"@type":"Thing","name":"Biomarkers of aging","sameAs":"https://en.wikipedia.org/wiki/Biomarkers_of_aging"},{"@type":"Thing","name":"Gerontology","sameAs":"https://en.wikipedia.org/wiki/Gerontology"},{"@type":"Thing","name":"Longevity","sameAs":"https://en.wikipedia.org/wiki/Longevity"},{"@type":"Thing","name":"Bioinformatics","sameAs":"https://en.wikipedia.org/wiki/Bioinformatics"},{"@type":"Thing","name":"Biotechnology","sameAs":"https://en.wikipedia.org/wiki/Biotechnology"},{"@type":"Thing","name":"Health policy","sameAs":"https://en.wikipedia.org/wiki/Health_policy"}],"sameAs":["https://x.com/agingbrief","https://www.linkedin.com/company/agingresearch-news"]},{"@type":"WebSite","@id":"https://agingresearch.news/#website","url":"https://agingresearch.news","name":"AgingResearch.News","alternateName":["Aging Research News","ARN"],"description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","inLanguage":"en","publisher":{"@id":"https://agingresearch.news/#organization"}}]}f:X 12:[["children",{"s":"__PAGE__","d":{"r":"$L13","p":false,"v":null}}]] 10:[["children",{"s":{"n":"key","t":"d","k":"tom-appleton","s":[]},"d":{"r":"$L11","p":false,"v":"$f"},"c":"$Q12"}]] d:[["children",{"s":"organisation","d":{"r":"$Le","p":false,"v":"$f"},"c":"$Q10"}],["sheet",{"s":"__DEFAULT__","d":{"r":"$L14","p":false,"v":null}}]] 0:{"P":null,"c":["","organisation","tom-appleton"],"q":"","i":false,"t":{"t":{"s":"","h":16,"d":{"r":["$","$L6","c",{"notFound":[[["$","link","0",{"rel":"stylesheet","href":"/_next/static/immutable/chunks/27vwfpponrsnz.css","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}],["$","link","1",{"rel":"stylesheet","href":"/_next/static/immutable/chunks/1-5e-kxoox4o1.css","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}],["$","script","script-0",{"src":"/_next/static/immutable/chunks/365b61on5mcg4.js","async":true,"nonce":"$undefined"}],["$","script","script-1",{"src":"/_next/static/immutable/chunks/1bdsvgxhdlloz.js","async":true,"nonce":"$undefined"}],["$","script","script-2",{"src":"/_next/static/immutable/chunks/3i6_rfhwrc4o0.js","async":true,"nonce":"$undefined"}],["$","script","script-3",{"src":"/_next/static/immutable/chunks/0f_7d7kh-cjld.js","async":true,"nonce":"$undefined"}]],["$","html",null,{"lang":"en","className":"_0coOsG_className ujwUxa_variable FJdxoa_variable","suppressHydrationWarning":true,"children":[["$","head",null,{"children":[["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var m=localStorage.getItem(\"arn.me\");if(m)document.documentElement.dataset.me=m}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var s=sessionStorage,n=performance.getEntriesByType(\"navigation\")[0],q;try{q=JSON.parse(s.getItem(\"arn.arrivals\")||\"[]\")}catch(e){}if(!Array.isArray(q))q=[];q.push({path:location.pathname,referrer:document.referrer,search:location.search,started:s.getItem(\"arn.visit\")===\"1\",again:!!n&&(n.type===\"reload\"||n.type===\"back_forward\")});s.setItem(\"arn.arrivals\",JSON.stringify(q.slice(-20)));s.setItem(\"arn.visit\",\"1\")}catch(e){}"}}],"$L7"]}],["$","body",null,{"className":"min-h-dvh bg-paper font-sans text-ink","children":[["$","a",null,{"href":"#content","className":"skip-link","children":"Skip to content"}],["$","script",null,{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"$8"}}],"$L9","$La","$Lb"]}]]}]],"children":["$0:t:t:d:r:props:notFound:0","$Lc"]}],"p":false,"v":null},"c":"$Qd"},"h":{"r":"$L15","p":false,"v":null}},"m":"$undefined","G":["$16",["$L17","$L18"]],"S":false,"r":"$undefined","s":"$undefined","a":"$undefined","l":"$undefined","p":"$undefined","d":"$undefined"} 19:I[684230,["$1","$2","$3","$4"],"MeProvider"] 1a:"/_next/static/immutable/chunks/1p2l5vb3-sh0r.js" 1b:"/_next/static/immutable/chunks/2uprp8m4908d0.js" 1c:I[432748,["$1","$2","$3","$4","$1a","$1b"],"Unplaced"] 1d:"/_next/static/immutable/chunks/2g0b2ejd_3ks5.js" 1e:"/_next/static/immutable/chunks/3lk5nyy6mb70i.js" 1f:I[675689,["$1","$2","$3","$4","$1d","$1b","$1e"],"Rail"] 20:I[435939,["$1","$2","$3","$4","$1d","$1b","$1e"],"SiteHeader"] 21:I[779780,["$1","$2","$3","$4","$1a","$1b"],"SearchIcon"] 22:I[522016,["$1","$2","$3","$4","$1d","$1b","$1e"],""] 2a:I[124213,["$1","$2","$3","$4"],"PageviewBeacon"] 2b:I[401529,["$1","$2","$3","$4"],"VitalsBeacon"] 31:"$Sreact.fragment" 32:I[339756,["$1","$2","$3","$4"],"default"] 33:I[837457,["$1","$2","$3","$4"],"default"] 35:I[897367,["$1","$2","$3","$4"],"OutletBoundary"] 37:"ViewportBoundary" 38:I[897367,["$1","$2","$3","$4"],"$37"] 3a:"MetadataBoundary" 3b:I[897367,["$1","$2","$3","$4"],"$3a"] 3c:"$Sreact.suspense" 9:["$","$L19",null,{"children":[[[],[["$","$L1c",null,{"children":["$","div",null,{"className":"frame","data-wide":"$undefined","children":[["$","$L1f",null,{"hint":"$undefined","updatesAt":"2026-10-12T22:42:00+01:00"}],["$","div",null,{"className":"frame-column min-w-0","children":[[["$","$L20",null,{"hint":"$undefined"}],["$","div",null,{"id":"content","tabIndex":-1,"className":"outline-none"}]],["$","main",null,{"className":"min-w-0 px-(--col-pad) lg:pb-16 pt-4 md:pt-5","children":[["$","header",null,{"className":"bleed flex items-end justify-between gap-6 border-b border-rule px-(--col-pad) pb-3","children":[["$","div",null,{"className":"min-w-0","children":["$undefined",["$","h1",null,{"className":"headline text-[22px] leading-[1.15] font-extrabold tracking-[-0.02em] text-ink","children":"Page not found"}],"$undefined"]}],"$undefined"]}],["$","p",null,{"className":"mt-4 text-[15px] leading-[1.4] text-pretty text-ink-soft","children":"There is no page at this address. The link may be old or mistyped."}],["$","form",null,{"action":"/search","method":"get","role":"search","aria-label":"Site","className":"relative mt-6 lg:hidden","children":[["$","span",null,{"aria-hidden":true,"className":"pointer-events-none absolute top-1/2 left-3.5 -translate-y-1/2 text-muted","children":["$","$L21",null,{"className":"size-[20px]"}]}],["$","input",null,{"name":"q","type":"search","inputMode":"search","enterKeyHint":"search","autoComplete":"off","autoCorrect":"off","autoCapitalize":"none","spellCheck":false,"maxLength":200,"placeholder":"Search papers, drugs, genes","aria-label":"Search aging research","className":"h-11 w-full appearance-none rounded-lg border-[1.5px] border-transparent bg-paper-deep pr-4 pl-11 text-[16px] text-ink transition-colors duration-[120ms] outline-none placeholder:text-muted focus:border-ink focus:bg-paper"}]]}],["$","ul",null,{"className":"mt-6","children":[["$","li","/",{"children":["$","$L22",null,{"href":"/","prefetch":false,"className":"bleed flex min-h-12 items-center border-b border-rule px-(--col-pad) text-[15px] font-bold transition-colors duration-[120ms] hover:bg-hover active:bg-pressed","children":"Home"}]}],["$","li","/latest",{"children":["$","$L22",null,{"href":"/latest","prefetch":false,"className":"bleed flex min-h-12 items-center border-b border-rule px-(--col-pad) text-[15px] font-bold transition-colors duration-[120ms] hover:bg-hover active:bg-pressed","children":"Latest"}]}],["$","li","/topics",{"children":["$","$L22",null,{"href":"/topics","prefetch":false,"className":"bleed flex min-h-12 items-center border-b border-rule px-(--col-pad) text-[15px] font-bold transition-colors duration-[120ms] hover:bg-hover active:bg-pressed","children":"Topics"}]}]]}]]}],["$","footer",null,{"className":"mt-16 border-t border-rule sm:mt-20 lg:hidden","children":["$","nav",null,{"aria-label":"Footer","className":"flex flex-wrap items-center gap-x-3.5 px-4 py-2 text-[13px] text-muted","children":[[["$","$L22","/privacy",{"href":"/privacy","className":"flex min-h-11 items-center transition-colors duration-[120ms] hover:text-ink","children":"Privacy"}],["$","$L22","/terms",{"href":"/terms","className":"flex min-h-11 items-center transition-colors duration-[120ms] hover:text-ink","children":"Terms"}],["$","$L22","/contact",{"href":"/contact","className":"flex min-h-11 items-center transition-colors duration-[120ms] hover:text-ink","children":"Contact"}],["$","$L22","/feeds",{"href":"/feeds","className":"flex min-h-11 items-center transition-colors duration-[120ms] hover:text-ink","children":"RSS"}]],["$","a",null,{"href":"https://x.com/agingbrief","target":"_blank","rel":"noopener","title":"Follow @agingbrief on X","className":"inline-flex items-center gap-1.5 min-h-11 transition-colors duration-[120ms] hover:text-ink","children":[["$","svg",null,{"viewBox":"0 0 1200 1227","aria-hidden":true,"className":"shrink-0 size-[11px]","fill":"currentColor","children":["$","path",null,{"d":"M714.163 519.284L1160.89 0H1055.03L667.137 450.887L357.328 0H0L468.492 681.821L0 1226.37H105.866L515.491 750.218L842.672 1226.37H1200L714.137 519.284H714.163ZM569.165 687.828L521.697 619.934L144.011 79.6944H306.615L611.412 515.685L658.88 583.579L1055.08 1150.3H892.476L569.165 687.854V687.828Z"}]}],"Follow on X"]}],"$L23"]}]}],"$L24"]}],"$L25"]}]}],"$9:props:children:0:0"]],"$undefined","$L26","$L27","$L28","$L29"]}] a:["$","$L2a",null,{}] b:["$","$L2b",null,{}] 2d:Tf7c,{"@context":"https://schema.org","@graph":[{"@type":"NewsMediaOrganization","@id":"https://agingresearch.news/#organization","name":"AgingResearch.News","alternateName":["Aging Research News","ARN"],"url":"https://agingresearch.news","logo":"https://agingresearch.news/logo.png","description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","slogan":"Every new aging paper, judged on evidence, never on fame.","foundingDate":"2026-10-02","parentOrganization":{"@type":"Organization","name":"Paperfoot AI Pte. Ltd.","address":{"@type":"PostalAddress","addressCountry":"SG"}},"publishingPrinciples":"https://agingresearch.news/status#standards","correctionsPolicy":"https://agingresearch.news/status#standards","ethicsPolicy":"https://agingresearch.news/status#standards","verificationFactCheckingPolicy":"https://agingresearch.news/status#standards","noBylinesPolicy":"https://agingresearch.news/status#standards","actionableFeedbackPolicy":"https://agingresearch.news/status#standards","contactPoint":{"@type":"ContactPoint","contactType":"editorial","url":"https://agingresearch.news/contact"},"knowsAbout":[{"@type":"Thing","name":"Aging","sameAs":"https://en.wikipedia.org/wiki/Ageing"},{"@type":"Thing","name":"Geroscience","sameAs":"https://en.wikipedia.org/wiki/Geroscience"},{"@type":"Thing","name":"Life extension","sameAs":"https://en.wikipedia.org/wiki/Life_extension"},{"@type":"Thing","name":"Cellular senescence","sameAs":"https://en.wikipedia.org/wiki/Cellular_senescence"},{"@type":"Thing","name":"Epigenetic clock","sameAs":"https://en.wikipedia.org/wiki/Epigenetic_clock"},{"@type":"Thing","name":"mTOR","sameAs":"https://en.wikipedia.org/wiki/MTOR"},{"@type":"Thing","name":"Rapamycin","sameAs":"https://en.wikipedia.org/wiki/Sirolimus"},{"@type":"Thing","name":"Cellular reprogramming","sameAs":"https://en.wikipedia.org/wiki/Reprogramming"},{"@type":"Thing","name":"NAD+","sameAs":"https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide"},{"@type":"Thing","name":"Sirtuins","sameAs":"https://en.wikipedia.org/wiki/Sirtuin"},{"@type":"Thing","name":"Mitochondria","sameAs":"https://en.wikipedia.org/wiki/Mitochondria"},{"@type":"Thing","name":"Calorie restriction","sameAs":"https://en.wikipedia.org/wiki/Calorie_restriction"},{"@type":"Thing","name":"GLP-1 receptor agonists","sameAs":"https://en.wikipedia.org/wiki/GLP-1_receptor_agonist"},{"@type":"Thing","name":"Inflammaging","sameAs":"https://en.wikipedia.org/wiki/Inflammaging"},{"@type":"Thing","name":"Brain aging","sameAs":"https://en.wikipedia.org/wiki/Aging_brain"},{"@type":"Thing","name":"Biological aging","sameAs":"https://en.wikipedia.org/wiki/Senescence"},{"@type":"Thing","name":"Geroprotectors","sameAs":"https://en.wikipedia.org/wiki/Geroprotector"},{"@type":"Thing","name":"Biomarkers of aging","sameAs":"https://en.wikipedia.org/wiki/Biomarkers_of_aging"},{"@type":"Thing","name":"Gerontology","sameAs":"https://en.wikipedia.org/wiki/Gerontology"},{"@type":"Thing","name":"Longevity","sameAs":"https://en.wikipedia.org/wiki/Longevity"},{"@type":"Thing","name":"Bioinformatics","sameAs":"https://en.wikipedia.org/wiki/Bioinformatics"},{"@type":"Thing","name":"Biotechnology","sameAs":"https://en.wikipedia.org/wiki/Biotechnology"},{"@type":"Thing","name":"Health policy","sameAs":"https://en.wikipedia.org/wiki/Health_policy"}],"sameAs":["https://x.com/agingbrief","https://www.linkedin.com/company/agingresearch-news"]},{"@type":"WebSite","@id":"https://agingresearch.news/#website","url":"https://agingresearch.news","name":"AgingResearch.News","alternateName":["Aging Research News","ARN"],"description":"AgingResearch.News is the superintelligence for aging research. It reads every new paper, weighs the evidence, cites every claim and fits a feed to your work.","inLanguage":"en","publisher":{"@id":"https://agingresearch.news/#organization"}}]}c:["$","html",null,{"lang":"en","className":"_0coOsG_className ujwUxa_variable FJdxoa_variable","suppressHydrationWarning":true,"children":[["$","head",null,{"children":[["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var m=localStorage.getItem(\"arn.me\");if(m)document.documentElement.dataset.me=m}catch(e){}"}}],["$","script",null,{"dangerouslySetInnerHTML":{"__html":"try{var s=sessionStorage,n=performance.getEntriesByType(\"navigation\")[0],q;try{q=JSON.parse(s.getItem(\"arn.arrivals\")||\"[]\")}catch(e){}if(!Array.isArray(q))q=[];q.push({path:location.pathname,referrer:document.referrer,search:location.search,started:s.getItem(\"arn.visit\")===\"1\",again:!!n&&(n.type===\"reload\"||n.type===\"back_forward\")});s.setItem(\"arn.arrivals\",JSON.stringify(q.slice(-20)));s.setItem(\"arn.visit\",\"1\")}catch(e){}"}}],"$L2c"]}],["$","body",null,{"className":"min-h-dvh bg-paper font-sans text-ink","children":[["$","a",null,{"href":"#content","className":"skip-link","children":"Skip to content"}],["$","script",null,{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"$2d"}}],"$L2e","$L2f","$L30"]}]]}] e:["$","$31","c",{"children":[null,["$","$L32",null,{"parallelRouterKey":"children","error":"$undefined","errorStyles":"$undefined","errorScripts":"$undefined","template":["$","$L33",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}]]}] 11:["$","$31","c",{"children":[null,["$","$L32",null,{"parallelRouterKey":"children","error":"$undefined","errorStyles":"$undefined","errorScripts":"$undefined","template":["$","$L33",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}]]}] 13:["$","$31","c",{"children":["$L34",[["$","script","script-0",{"src":"/_next/static/immutable/chunks/2g0b2ejd_3ks5.js","async":true,"nonce":"$undefined"}],["$","script","script-1",{"src":"/_next/static/immutable/chunks/2uprp8m4908d0.js","async":true,"nonce":"$undefined"}],["$","script","script-2",{"src":"/_next/static/immutable/chunks/3lk5nyy6mb70i.js","async":true,"nonce":"$undefined"}]],["$","$L35",null,{"children":"$@36"}]]}] 14:["$","$31","c",{"children":[null,null,null]}] 15:["$","$31","h",{"children":[null,["$","$L38",null,{"children":"$L39"}],["$","$L3b",null,{"children":[["$","div",null,{"hidden":true,"children":["$","$3c",null,{"name":"Next.Metadata","children":"$L3d"}]}],"$L3e"]}],["$","meta",null,{"name":"next-size-adjust","content":""}]]}] 17:["$","link","0",{"rel":"stylesheet","href":"/_next/static/immutable/chunks/27vwfpponrsnz.css","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}] 18:["$","link","1",{"rel":"stylesheet","href":"/_next/static/immutable/chunks/1-5e-kxoox4o1.css","precedence":"next","crossOrigin":"$undefined","nonce":"$undefined"}] 3f:I[149277,["$1","$2","$3","$4","$1d","$1b","$1e"],"FoundingBar"] 40:I[936821,["$1","$2","$3","$4"],"AuthHost"] 41:I[188415,["$1","$2","$3","$4"],"BottomTabBar"] 42:I[233785,["$1","$2","$3","$4"],"FeedTracker"] 43:I[696255,["$1","$2","$3","$4"],"NavMemory"] 44:"/_next/static/immutable/chunks/09f4ck8c_bo21.js" 45:I[408821,["$1","$2","$3","$4","$44"],"default"] f:C 23:["$","span",null,{"children":["© ",2026," AgingResearch.News"]}] 24:["$","$L3f",null,{"until":"2026-10-20T22:59:59.000Z"}] 26:["$","$L40",null,{"oneTapClientId":"1014590465548-acrir82hrkhsm9kpku98fp77435bh7qo.apps.googleusercontent.com"}] 27:["$","$L41",null,{}] 28:["$","$L42",null,{}] 29:["$","$L43",null,{}] 2e:["$","$L19",null,{"children":[["$","$L32",null,{"parallelRouterKey":"children","error":"$45","errorStyles":[],"errorScripts":[["$","script","script-0",{"src":"/_next/static/immutable/chunks/09f4ck8c_bo21.js","async":true,"nonce":"$undefined"}]],"template":["$","$L33",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$9:props:children:0:1","forbidden":"$undefined","unauthorized":"$undefined"}],["$","$L32",null,{"parallelRouterKey":"sheet","error":"$45","errorStyles":"$2e:props:children:0:props:errorStyles","errorScripts":"$2e:props:children:0:props:errorScripts","template":["$","$L33",null,{}],"templateStyles":"$undefined","templateScripts":"$undefined","notFound":"$undefined","forbidden":"$undefined","unauthorized":"$undefined"}],["$","$L40",null,{"oneTapClientId":"1014590465548-acrir82hrkhsm9kpku98fp77435bh7qo.apps.googleusercontent.com"}],["$","$L41",null,{}],["$","$L42",null,{}],["$","$L43",null,{}]]}] 2f:["$","$L2a",null,{}] 30:["$","$L2b",null,{}] 39:[["$","meta","0",{"charSet":"utf-8"}],["$","meta","1",{"name":"viewport","content":"width=device-width, initial-scale=1, viewport-fit=cover"}],["$","meta","2",{"name":"theme-color","content":"#ffffff","media":"(prefers-color-scheme: light)"}],["$","meta","3",{"name":"theme-color","content":"#242424","media":"(prefers-color-scheme: dark)"}],["$","meta","4",{"name":"color-scheme","content":"light dark"}]] 46:I[545892,["$1","$2","$3","$4","$1d","$1b","$1e"],"SidebarSearch"] 47:I[43816,["$1","$2","$3","$4","$1d","$1b","$1e"],"StickyRail"] 48:I[892174,["$1","$2","$3","$4","$1d","$1b","$1e"],"HideOn"] 49:I[605500,["$1","$2","$3","$4","$1d","$1b","$1e"],"Image"] 4a:I[743237,["$1","$2","$3","$4","$1d","$1b","$1e"],"IntentLink"] 25:["$","aside",null,{"aria-label":"Sidebar","className":"sidebar hidden lg:block","children":[["$","$L46",null,{}],["$","$L47",null,{"className":"space-y-3.5 pt-2 pb-10","children":[["$","$L48",null,{"section":"/news","children":["$","section",null,{"aria-labelledby":"rail-news","className":"module","children":[["$","div",null,{"className":"module-head","children":[["$","h2",null,{"id":"rail-news","className":"module-title","children":"News"}],["$","$L22",null,{"href":"/news","aria-label":"See all news","className":"module-more","children":"See all"}]]}],[["$","a","879",{"href":"https://news.google.com/rss/articles/CBMiWEFVX3lxTE00bkpuaVVzWDBVQkU0bnBILWlhM3FXNVdrME9vREJ4VzVnNUE4OFNQNzRRWWJfTHVOVmx1cW9SM09zaEZ0b25pT1JuMFR2dWJNbE9qQzAxbE0?oc=5","target":"_blank","rel":"noopener","className":"module-row grid grid-cols-[minmax(0,1fr)_auto] items-start gap-3","children":[["$","span",null,{"className":"min-w-0","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Korea University secures ₩8.3 billion for AI-assisted gut microbiota-derived rejuvenation drug development"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Funding"}],["$","span",null,{"className":"min-w-0","children":"healtho.co.kr and 3 more"}]]}]]}],["$","$L49",null,{"src":"/img/news-879/b36a2b03.jpg","alt":"","width":48,"height":48,"sizes":"48px","loading":"lazy","draggable":false,"className":"size-12 rounded-lg bg-paper-deep object-cover"}]]}],["$","a","971",{"href":"https://www.nature.com/articles/s41591-026-04614-0","target":"_blank","rel":"noopener","className":"module-row grid grid-cols-[minmax(0,1fr)_auto] items-start gap-3","children":[["$","span",null,{"className":"min-w-0","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Researchers report abrupt multisystem physiological shifts when women have their last menstrual period"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Research"}],["$","span",null,{"className":"min-w-0","children":"Nature Medicine and 3 more"}]]}]]}],["$","$L49",null,{"src":"/fig/news-4893/752a51aa.webp","alt":"","width":48,"height":48,"sizes":"48px","loading":"lazy","draggable":false,"className":"size-12 rounded-lg bg-paper-deep object-cover"}]]}],["$","a","433",{"href":"https://www.genengnews.com/topics/omics/secrets-of-oldest-land-animals-194-year-lifespan-revealed-with-epigenetics/","target":"_blank","rel":"noopener","className":"module-row grid grid-cols-[minmax(0,1fr)_auto] items-start gap-3","children":[["$","span",null,{"className":"min-w-0","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Jonathan, the 194-year-old tortoise, shows stable epigenetic regulation of metabolism and DNA repair"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Research"}],["$","span",null,{"className":"min-w-0","children":"GEN and 7 more"}]]}]]}],["$","$L49",null,{"src":"/fig/news-2056/821ac05e.jpg","alt":"","width":48,"height":48,"sizes":"48px","loading":"lazy","draggable":false,"className":"size-12 rounded-lg bg-paper-deep object-cover"}]]}]]]}]}],["$","$L48",null,{"section":"/trials","children":["$","section",null,{"aria-labelledby":"rail-trials","className":"module","children":[["$","div",null,{"className":"module-head","children":[["$","h2",null,{"id":"rail-trials","className":"module-title","children":"Trials"}],["$","$L22",null,{"href":"/trials","aria-label":"See all trials","className":"module-more","children":"See all"}]]}],[["$","$L4a","NCT07861867",{"href":"/trials/NCT07861867","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"AKG and Brain Health in Aging"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":["$L4b","$L4c"]}]]}],"$L4d","$L4e"]]}]}],"$L4f","$L50","$L51"]}]]}] 4b:["$","span",null,{"title":"$undefined","className":"tag","children":"Phase 2"}] 4c:["$","span",null,{"className":"min-w-0","children":"Registered 6 Oct 2026, University of Oklahoma"}] 4d:["$","$L4a","NCT07856602",{"href":"/trials/NCT07856602","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Phase 1"}],["$","span",null,{"className":"min-w-0","children":"Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene Technology"}]]}]]}] 4e:["$","$L4a","NCT07862933",{"href":"/trials/NCT07862933","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"AI-Based Conversational Social Support for Older Adults With Heart Failure"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":["",["$","span",null,{"className":"min-w-0","children":"Registered 7 Oct 2026, Chang Gung University of Science and Technology"}]]}]]}] 4f:["$","$L48",null,{"section":"/search","children":["$","section",null,{"aria-labelledby":"rail-trending","className":"module","children":[["$","div",null,{"className":"module-head","children":[["$","h2",null,{"id":"rail-trending","className":"module-title","children":"Trending"}],["$","$L22",null,{"href":"/trending","aria-label":"See all trending stories","className":"module-more","children":"See all"}]]}],[["$","$L22","/disease/menopause",{"href":"/disease/menopause","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Menopause"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Disease"}],["$","span",null,{"className":"min-w-0","children":"15 papers this week, usually 1"}]]}]]}],["$","$L22","/intervention/nicotinamide-riboside",{"href":"/intervention/nicotinamide-riboside","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Nicotinamide riboside"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Intervention"}],["$","span",null,{"className":"min-w-0","children":"Nicotinamide riboside did not improve early Parkinson disease"}]]}]]}],["$","$L22","/intervention/pregnancy",{"href":"/intervention/pregnancy","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Pregnancy"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Exposure"}],["$","span",null,{"className":"min-w-0","children":"Estimated brain-age gap rises by three years in pregnancy"}]]}]]}],["$","$L22","/intervention/lifestyle",{"href":"/intervention/lifestyle","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Lifestyle"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Exposure"}],["$","span",null,{"className":"min-w-0","children":"Genetic risk and lifestyle linked to estimated brain aging"}]]}]]}],["$","$L22","/disease/depressive-symptom",{"href":"/disease/depressive-symptom","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Depressive symptoms"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Disease"}],["$","span",null,{"className":"min-w-0","children":"23 papers this week, usually 4"}]]}]]}],["$","$L22","/intervention/vitamin-d",{"href":"/intervention/vitamin-d","className":"module-row","children":[["$","span",null,{"className":"block text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Vitamin D"}],["$","span",null,{"className":"mt-1 flex items-start gap-1.5 text-[13px] leading-5 text-muted","children":[["$","span",null,{"title":"$undefined","className":"tag","children":"Intervention"}],["$","span",null,{"className":"min-w-0","children":"Severe vitamin D deficiency is linked to higher death rates"}]]}]]}]]]}]}] 50:["$","section",null,{"aria-labelledby":"rail-topics","className":"module","children":[["$","div",null,{"className":"module-head","children":[["$","h2",null,{"id":"rail-topics","className":"module-title","children":"Topics"}],["$","$L22",null,{"href":"/topics","aria-label":"See all topics","className":"module-more","children":"See all"}]]}],[["$","$L22","mechanisms",{"href":"/topics/mechanisms","className":"module-row flex items-baseline justify-between gap-4","children":[["$","span",null,{"className":"min-w-0 text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Mechanisms"}],["$","span",null,{"className":"shrink-0 tabular-nums text-[13px] leading-5 text-muted","children":"243"}]]}],["$","$L22","interventions",{"href":"/topics/interventions","className":"module-row flex items-baseline justify-between gap-4","children":[["$","span",null,{"className":"min-w-0 text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Interventions"}],["$","span",null,{"className":"shrink-0 tabular-nums text-[13px] leading-5 text-muted","children":"454"}]]}],["$","$L22","biomarkers",{"href":"/topics/biomarkers","className":"module-row flex items-baseline justify-between gap-4","children":[["$","span",null,{"className":"min-w-0 text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Biomarkers"}],["$","span",null,{"className":"shrink-0 tabular-nums text-[13px] leading-5 text-muted","children":"435"}]]}],["$","$L22","populations",{"href":"/topics/populations","className":"module-row flex items-baseline justify-between gap-4","children":[["$","span",null,{"className":"min-w-0 text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Populations"}],["$","span",null,{"className":"shrink-0 tabular-nums text-[13px] leading-5 text-muted","children":"598"}]]}],["$","$L22","ai-data",{"href":"/topics/ai-data","className":"module-row flex items-baseline justify-between gap-4","children":[["$","span",null,{"className":"min-w-0 text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"AI & data"}],["$","span",null,{"className":"shrink-0 tabular-nums text-[13px] leading-5 text-muted","children":"169"}]]}],["$","$L22","industry-policy",{"href":"/topics/industry-policy","className":"module-row flex items-baseline justify-between gap-4","children":[["$","span",null,{"className":"min-w-0 text-[15px] leading-[1.25] font-bold tracking-[-0.005em] text-ink","children":"Industry & policy"}],["$","span",null,{"className":"shrink-0 tabular-nums text-[13px] leading-5 text-muted","children":"23"}]]}]]]}] 51:["$","nav",null,{"aria-label":"Footer","className":"px-1","children":["$","ul",null,{"className":"flex flex-wrap gap-x-3.5 gap-y-1 text-[13px] leading-5 text-muted","children":[[["$","li","/privacy",{"children":["$","$L22",null,{"href":"/privacy","className":"transition-colors duration-[120ms] hover:text-ink","children":"Privacy"}]}],["$","li","/terms",{"children":["$","$L22",null,{"href":"/terms","className":"transition-colors duration-[120ms] hover:text-ink","children":"Terms"}]}],["$","li","/contact",{"children":["$","$L22",null,{"href":"/contact","className":"transition-colors duration-[120ms] hover:text-ink","children":"Contact"}]}],["$","li","/feeds",{"children":["$","$L22",null,{"href":"/feeds","className":"transition-colors duration-[120ms] hover:text-ink","children":"RSS"}]}]],["$","li",null,{"children":["$","a",null,{"href":"https://x.com/agingbrief","target":"_blank","rel":"noopener","title":"Follow @agingbrief on X","className":"inline-flex items-center gap-1.5 transition-colors duration-[120ms] hover:text-ink","children":[["$","svg",null,{"viewBox":"0 0 1200 1227","aria-hidden":true,"className":"shrink-0 size-[11px]","fill":"currentColor","children":["$","path",null,{"d":"M714.163 519.284L1160.89 0H1055.03L667.137 450.887L357.328 0H0L468.492 681.821L0 1226.37H105.866L515.491 750.218L842.672 1226.37H1200L714.137 519.284H714.163ZM569.165 687.828L521.697 619.934L144.011 79.6944H306.615L611.412 515.685L658.88 583.579L1055.08 1150.3H892.476L569.165 687.854V687.828Z"}]}],"Follow on X"]}]}],["$","li",null,{"children":["© ",2026," AgingResearch.News"]}]]}]}] 52:T5d5,(function(c){try{var d=document.documentElement,i,j,K=/^[a-z0-9-]{1,40}$/,own=function(o,k){return Object.prototype.hasOwnProperty.call(o,k)};for(i=0;i

Tom Appleton

Trials