Office of Research Infrastructure Programs

• Phosphodiesterase 4 inhibitors extend lifespan of C. elegans and attenuate cellular senescence of mouse embryonic fibroblasts

  P40 OD011440, 8 Oct 2026

• USP-48 enables insulin-mediated longevity and modulates the mitochondrial stress response

  P40 OD010440, 30 Sept 2026

• Elevated mitochondrial superoxide promotes longevity through a mitochondria-to-nucleus kinase signaling pathway

  P30 OD010440, 8 Sept 2026

• The Arlington study of healthy aging: a multidisciplinary community cohort study of functional decline with age

  S10OD028472, 28 Aug 2026

• An in vivo resource of age-regulated C. elegans intestinal secretory-pathway proteins highlights secreted enzymes associated with lifespan regulation

  P40 OD010440, 27 Aug 2026

• Form and function of actin impacts actin health and aging

  P40 OD010440, 24 Aug 2026

• Physiological effects of pear (Pyrus pyrifolia var. culta) leaf extract on Caenorhabditis elegans

  P40 OD010440, 19 Aug 2026

• Self-Organizing Ovarian Somatic Organoids Preserve Cellular Heterogeneity and Reveal Cellular Contributions to Ovarian Aging

  P51 OD011092, 1 Jan 2026

• Aging-linked systemic lipid signature is reprogrammed by caloric restriction in rhesus monkeys

  P51OD011106, 10 Dec 2025

• Enhancing Late-Life Survival and Mobility via Mitohormesis by Reducing Mitochondrial Calcium Levels

  26 Sept 2025

• The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

  P40OD010440, 23 Sept 2025

• Protein disulfide isomerase PDI-6 regulates Wnt secretion to coordinate inter-tissue UPRmt activation and lifespan extension in C. elegans

  P40 OD010440, 7 Jun 2022

• Fasting blood glucose as a predictor of mortality: Lost in translation

  P51OD011106, P51RR000167, 10 Sept 2021

Sources: api.crossref.org